SCORE2-Asia-Pacific

This function calculates the 10-year cardiovascular risk estimation for patients aged 40 to 69 years using the doi:10.1093/eurheartj/ehae609 SCORE2-Asia-Pacific algorithm. Risk score is expressed as percentage in one decimal place. It also categorises these patients into different risk groups.

Usage

SCORE2_Asia_Pacific(
  Risk.region,
  Age,
  Gender,
  smoker,
  systolic.bp,
  total.chol,
  total.hdl,
  diabetes,
  classify = FALSE
)

Arguments

Risk.region

Input character to indicate an Asian or Oceania risk region group the patient belongs to. The allowed categories are

• Low

• Moderate

• High

• Very high

Age

Input positive integer to indicate the age of the patient.

Gender

Input character to indicate the gender of the patient. The allowed categories are

• male

• female

smoker

Input integer 0 or 1 to indicate if the patient is a current smoker.

• 0 stands for patient is either a former/past smoker or a non-smoker.

• 1 stands for patient is a current smoker.

systolic.bp

Input positive numeric value to indicate the patient's systolic blood pressure in \(mm HG\).

total.chol

Input positive numeric value to indicate the patient's total cholesterol in \(mmol/L\).

total.hdl

Input positive numeric value to indicate the patient's high-density lipoprotein (HDL) in \(mmol/L\).

diabetes

Input integer 0 or 1 to indicate if the patient has diabetes.

• 0 stands for not having diabetes.

• 1 stands for having diabetes.

classify

When set to TRUE, the function will return the patient's risk group based on the SCORE2-Asia-Pacific risk score in percentage rounded to one decimal place. Default: FALSE.

Risk groups are classified based on Figure 3 from the doi:10.1093/eurheartj/ehad192 2023 ESC Guidelines for the management of cardiovascular disease in patients with diabetes:

SCORE2-Asia-Pacific Score	10-year Cardiovascular Disease (CVD) Risk Group
\(<5\%\)	Low risk
\(5\%\) to \(<10\%\)	Moderate risk
\(10\%\) to \(<20\%\)	High risk
\(\ge20\%\)	Very high risk

Value

SCORE2-Asia-Pacific doi:10.1093/eurheartj/ehae609 risk score expressed as a positive percentage rounded to one decimal place when classify is FALSE. A patient's risk group when classify is TRUE.

Details

SCORE2-Asia-Pacific doi:10.1093/eurheartj/ehae609 was developed by extending the SCORE2 doi:10.1093/eurheartj/ehab309 algorithms using 8405574 participants (556421 CVD events) from the Asia-Pacific regions without previous CVD.

References

Primary Paper

• SCORE2 Asia-Pacific writing group, Hageman SHJ, Huang Z, Lee H, Kaptoge S, Dorresteijn JAN, Pennells L, Angelantonio ED, Visseren FLJ, Hyeon CK, Johar A, the European Society of Cardiology and European Association of Preventive Cardiology: Cardiovascular Risk Collaboration (ESC CRC), the ASEAN Federation of Cardiology (AFC), the Asian-Pacific Society of Cardiology (APSC), on behalf of the SCORE2 Asia-Pacific collaborators, SCORE2-Diabetes: 10-year cardiovascular risk estimation in type 2 diabetes in Europe, Eur Heart J, 44:2544–2556, doi:10.1093/eurheartj/ehad260

Clinical Practice Guidelines

• Marx N, Federici M, Schütt K, Müller-Wieland D, Ajjan RA,vAntunes MJ, Christodorescu RM, Crawford C, Angelantonio ED, Eliasson B, Espinola-Klein C, Fauchier L, Halle M, Herrington WG, Kautzky-Willer A, Lambrinou E, Lesiak M, Lettino M, McGuire DK, Mullens W, Rocca B, Sattar N, ESC Scientific Document Group, 2023 ESC Guidelines for the management of cardiovascular disease in patients with diabetes: Developed by the task force on the management of cardiovascular disease in patients with diabetes of the European Society of Cardiology (ESC), Eur Heart J, 44:4043–4140, doi:10.1093/eurheartj/ehad192

Examples

# 50 years old male from low risk region
# who is a smoker, non-diabetic
# with a systolic blood pressure of 140 mmHg,
# total cholesterol of 5.5 mmol/L,
# HDL cholesterol of 1.3 mmol/L,
# will have a risk score of 10.3 and
# at high risk of CVD.

SCORE2_Asia_Pacific(
  Risk.region = "Low",
  Age = 50,
  Gender = "male",
  smoker = 1,
  systolic.bp = 140,
  total.chol = 5.5,
  total.hdl = 1.3,
  diabetes = 0,
  classify = FALSE
)
#> [1] 10.3

SCORE2_Asia_Pacific(
  Risk.region = "Low",
  Age = 50,
  Gender = "male",
  smoker = 1,
  systolic.bp = 140,
  total.chol = 5.5,
  total.hdl = 1.3,
  diabetes = 0,
  classify = TRUE
)
#> [1] "High risk"